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| Тема |
 Gonal-F |
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| Автор |
mery_ (брюнетка) |
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| Публикувано | 16.05.02 08:02 |
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Gonal-F® (follitropin alfa for injection), a follicle stimulating hormone (FSH) that applies recombinant DNA (rDNA) technology to the treatment of fertility.
Serono Laboratories also introduced Fertinex™ (urofollitropin for injection, purified), the first gonadotropin pure enough to be self-administered by subcutaneous injection. Like Fertinex™, Gonal-F® is a breakthrough in fertility treatment. Now Gonal-F® a medication with the consistently high quality assurance only available through rDNA technology, can be part of your treatment regimen.
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QUESTIONS & ANSWERS
What hormones are needed to develop and release an egg?
Gonadotropin-releasing hormone (GnRH) is a hormone produced by the hypothalamus. It is responsible for releasing the proper amount A FSH and luteinizing hormone (LH) produced by the pituitary gland. FSH and LH control the development and release of an egg from the ovaries. Estrogen is produced by the ovaries and is responsible for the preparation of the endometrium, as well as the implantation and nutrition of a fertilized egg.
Why has my physician prescribed Gonal-F® (follitropin alfa for injection)?
FSH is the hormone that is primarily responsible for stimulating the development of follicles containing eggs Your physician has, prescribed Gonal-F ® to stimulate follicular development. Gonal-F® is a highly pure FSH.
What is Gonal-F®?
Gonal-F® is a highly pure and consistent FSH that is of the same high quality every time. It is the first FSH to he produced by rDNA technology. In the early 1980s, Serono scientists in the United States pioneered the technology used to produce Gonal-F. A further 12 years of research arid development were dedicated before making it available to you. Gonal-F® has been extensively tested in both the United States and Europe and has already been used by thousands of people worldwide
What are the advantages of rDNA technology?
High quality and purity arc the great advantages of this technology With the development of Gonal-F®, the gene that makes natural FSH has first isolated in the laboratory. Then, a highly controlled manufacturing process ensures consistent product quality every time.
How does Gonal-F® work?
The development and release of an egg from the ovaries is controlled by FSH and LH, which are both released from the pituitary gland in the brain. Gonal-F® acts directly on the ovaries to help stimulate the development of follicles.
How often and for how long will I need to take Gonal-F®?
Gonal-F® is administered daily. The length of treatment per cycle varies from patient to patient and is determined by your individual response to Gonal-F®
How is Gonal-F® administered?
Gonal-F® comes in an ampule that contains powder which needs to be mixed (reconstituted) with sterile water. Gonal-F® is given with all easy subcutaneous (SC) injection that allows for self-administration, helping to make your treatment more convenient and comfortable. Some other preparations are given intramuscularly (IM) with larger needles that must be injected deep within muscle tissues. Because of the nature of IM infections, you may he asked to receive those injections at the doctor's office, or have your Partner or a friend administer the injections.
Where should Gonal-F® be injected?
Because Gonal-F® is injected subcutaneously, yon will be able to administer it yourself Your fertility team will advise of the proper injection sites. Usual injection sites are the abdomen upper arm, or the thigh. You may wish to ask your fertility team for the Serono booklet and videotape that describe the proper methods of preparing and administering injections or call I -800-801-5170.
How safe and effective is Gonal-F® (follitropin alfa for injection)?
Gonal-F® is the only recombinant FSH preparation that has been extensively tested in both the United States and Europe. It has been proven safe and effective in clinical trials. Results of fertility therapy vary from patient to patient and cycle to cycle, depending on man) factors, including the cause of infertility, patient age, and the type of treatment used. You should ask your physician about the likelihood of conceiving with Gonal-F®.
How and why is therapy with Gonal-F® monitored and adjusted?
Your doctor will carefully monitor your response to Gonal-F®. Generally, therapy is monitored by measuring estrogen levels in the blood and by taking frequent ultrasound pictures of your ovaries to assess follicular development. Monitoring how you respond to Gonal-F® will help your doctor determine an individualized treatment regiment that is right for you.
Are there any side effects associated with the use of Gonal-F®?
As with all other FSH preparations, side effects can occur with the use of Gonal-F'. Ask your fertility team to discuss the possible side effects with you. As with all medications, it is important to report any physical changes and all symptoms to your doctor.
Is Gonal-F® associated with multiple births?
Reports of multiple births have been associated with all fertility treatments. You should discuss the potential risk of multiple births with your fertility team before beginning treatment.
Is Gonal-F® associated with congenital birth defects?
The incidence of birth defects associated with Gonal-F® is no different from that of the untreated population.
When is Gonal-F® the right choice for me?
Several options are available for fertility treatment and your doctor will tell you if Gonal-F' is right for you. Because Gonal-F® is produced by rDNA technology, it provides consistent quality and purity. In addition, Gonal-F® can be given by SC injection, making treatment much easier, more comfortable, and a less stressful choice.
Съдбата води желаещия, нежелаещия влачи!
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