Transgenic DNA is different from natural DNA and more likely to spread
Regulators frequently dismiss our concerns with remarks such as “The safety of nucleic acids is widely accepted. Both RNA and DNA are part of all food products that we consume. “ [6] (USDA FONSI for Transgenic Poplars Absurd & Dangerous, SiS 38). The implication is that transgenic DNA (or RNA) is no different from natural nucleic acids, and hence no more likely to spread by horizontal gene transfer.

There is no doubt that transgenic DNA is different from natural DNA; not only does it contain new combinations of genes, but also new synthetic genes that have never existed in billions of years of evolution: new coding sequences, promoters and other non-coding regulatory sequences that boost gene expression to abnormally high levels.

Furthermore, there are indeed reasons to suspect transgenic DNA is more likely to transfer horizontally and recombine than natural DNA (see Box adapted from [7] Living with the Fluid Genome, ISIS publication), and this has been borne out by accumulating evidence, even though dedicated research is still extremely rare.

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