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| Тема |
 Re: Civilizatoze [re: Dara of Amber] |
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| Автор |
Dara of Amber () |
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| Публикувано | 26.06.13 23:08 |
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HPV - Човешки папиломен вирус - предизвиква рак на матката
Phase III trials have been conducted, including over 18,000 women from 14 countries in Pacific Asia, Europe, Latin America and North America.[5]
As of 2009 the manufacturer was conducting a trial to compare the immunogenicity and safety of Cervarix with Gardasil.[6] Subsequent studies showed Cervarix generated higher antibody levels than Gardasil, the other commercally available HPV vaccine, upon testing seven months later, with twice the level for HPV type 16 and six times for HPV type 18.[citation needed] In addition Cervarix induced twice as many memory B cells as Gardasil for both these HPV strains.
Indications[edit]
HPV is a virus, usually transmitted sexually, which can cause cervical cancer in a small percentage of those women genital infected. Cervarix is a preventative HPV vaccine, not therapeutic. HPV immunity is type-specific, so a successful series of Cervarix shots will not block infection from cervical cancer-causing HPV types other than HPV types 16 and 18 and some related types, so experts continue to recommend routine cervical Pap smears even for women who have been vaccinated. Vaccination alone, without continued screening, would prevent fewer cervical cancers than regular screening alone.[7][8]
Cervarix is indicated for the prevention of the following diseases caused by oncogenic HPV types 16 and 18: cervical cancer, cervical intraepithelial neoplasia (CIN) grade 2 or worse and adenocarcinoma in situ, and CIN grade 1. Cervarix is approved for use in females 10 through 25 years of age.[9]
Limitations of effectiveness[edit]
Cervarix does not provide protection against disease due to all HPV types, nor against disease if a woman has previously been exposed through sexual activity and protection may not be obtained by all recipients.[9] It is therefore recommended that women continue to adhere to cervical cancer screening procedures.
Adverse effects[edit]
The most common local adverse reactions in ≥20% of patients were pain, redness, and swelling at the injection site.
The most common general adverse events in ≥20% of subjects were fatigue, headache, muscle pain (myalgia), gastrointestinal symptoms, and joint pain (arthralgia).[9]
The best way to find yourself is to lose yourself in the service of others.Mahatma Gandhi
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